Former Spice Girl Melanie C will join boogie-woogie star Jools Holland in a live show in the Villa Marina, Douglas, in July.
Jools first performed on the Isle of Man at Peel Castle in 2000. Ticket-holders had to queue all the way round Peel harbour to get in.
Subsequent Isle of Man shows by Jools have included special guest appearances by Marc Almond and Alison Moyet.
Melanie C (‘Sporty Spice’) sold more than 100 million albums with nineties group the Spice Girls and more than 12 million albums as a solo artist.
For the show on July 23, Jools will be joined on stage by the 20-piece Rhythm an Blues Orchestra, including pianist, organist, legendary drummer (Gilson Lavis), three female vocalists, including Ruby Turner, Louise Marshall and Mabel Ray, guitar, bass guitar, two tenor saxophones, two alto saxophones, baritone saxophone, three trumpets and four trombones.
The JHRBO plays to live audiences of more than 300,000 each year.
Tickets priced at £42.50 (including 2 per cent booking fee) are available from the Villa Box Office on 600555 from tomorrow (Saturday) at 9am.